John P . Forman and Walter C . Willett Nutrient - Wide Association Studies : Another Road to the Same Destination
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چکیده
Apart from the specific findings of this analysis, the authors encourage the use of what they call a nutrientwide association study, analogous to a genome-wide association study (GWAS), to investigate dietary determinants of health outcomes.1 Similar to the agnostic approach used in a GWAS, the features of their approach include the following: (1) the inclusion of all available nutrient exposures; (2) nonincorporation of previous knowledge; (3) adjustment of statistical tests for multiple comparisons; (4) division of the primary data set into training and test subsets; and (5) the use of a confirmatory data set. The primary objectives are to analyze all of the possible nutrient-disease hypotheses and to avoid false-positive conclusions.
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Nutrient - Wide Association Studies : Another Road to the Same Destination Running title :
Kidney Clini ica ca cal l l Re Re Rese se s ar ar a ch c c I I Ins ns nsti t tu tu ute te te
متن کاملNutrient-wide association studies: another road to the same destination.
Kidney Clini ica ca cal l l Re Re Rese se s ar ar a ch c c I I Ins ns nsti t tu tu ute te te
متن کاملEditorial Nutrient - Wide Association Studies Another Road to the Same Destination
Apart from the specific findings of this analysis, the authors encourage the use of what they call a nutrientwide association study, analogous to a genome-wide association study (GWAS), to investigate dietary determinants of health outcomes.1 Similar to the agnostic approach used in a GWAS, the features of their approach include the following: (1) the inclusion of all available nutrient exposur...
متن کاملAuthor's response to reviews Title:Joint association between birth weight at term and later life adherence to a healthy lifestyle with risk of hypertension: A prospective cohort study Authors:
Yanping Li Dr. ([email protected]) Sylvia H. Ley Dr. ([email protected]) Tyler J. VanderWeele Dr. ([email protected]) Gary C. Curhan Dr. ([email protected]) Janet W. Rich-Edwards Dr. ([email protected]) Walter C. Willett Dr. ([email protected]) John P. Forman Dr. ([email protected]) Frank B. Hu Dr. ([email protected]) Lu Qi Dr. (luqi@hs...
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